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NCT02 induces ubiquitination of cyclin K (CCNK) and proteasomal degradation of CCNK and its complex partner CDK12
2-²H3)acetamido]benzoate CAS Number n/a Related CAS Molecular Formula C10H11NO3 Molecular Weight 196
HQ461-mediated degradation of cyclin K impairs CDK12 function
918 Purity (HPLC) >= 95% Solubility DMSO
ZXH-1-161 deuterium-labeled-nitrogen NCT02 induces ubiquitination of cyclinZXH 1 161 is a potent cereblon (CRBN) modulator with an IC50 value of 39 nM in MM1. S wild type cells. ZXH 1 161 has selective degradation activity towards GSPT1. ZXH 1 161 can be used for researching multiple myeloma. Product Name ZXH 1 161 Synonyms CAS Number 2407654 51 5 Related CAS Molecular Formula C26H24N6O3 Molecular Weight 468. 517 SMILES O=C1N(CC2=C1C=CC=C2NC1=NC(NC2=CC3=C(CCC3)C=C2)=NC=C1)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Physical
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